Medicine · Pulmonology (Asthma, COPD, Tuberculosis, Pneumonia, ILD, Pleural Diseases)

A 52-year-old smoker with COPD has FEV1/FVC 0.61 (post-BD), FEV1 42% predicted, 3 exacerbations in the past year (2 requiring hospitalisation), and significant dyspnoea (mMRC grade 3). According to GOLD 2023, what is his GOLD group classification?

  • A GOLD group D
  • B GOLD group E
  • C GOLD group C
  • D GOLD group B
Correct answer: B. GOLD group E

Explanation

GOLD 2023 reclassified patients with ≥2 moderate exacerbations or ≥1 exacerbation requiring hospitalisation in the past year into a new high-risk 'Group E' (for Exacerbations), replacing the former A/B/C/D system. Patients in Group E, regardless of symptom burden, require LAMA + LABA ± ICS (triple therapy is indicated when blood eosinophils ≥300 cells/µL or exacerbations persist despite dual bronchodilation). This patient qualifies for Group E due to 2 hospitalisations (one hospitalisation ≥ 2 moderate exacerbations).

Reference: Harrison's Principles of Internal Medicine, 21st ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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