A 22-year-old woman presents with progressive behavioral disturbance, seizures, dyskinesias, and decreased consciousness. CSF shows lymphocytic pleocytosis. Anti-NMDA receptor antibodies are positive. Imaging should specifically evaluate for which associated finding?
- A Ovarian teratoma ✓
- B Cerebellar hemangioblastoma
- C Pituitary macroadenoma
- D Thymic hyperplasia
Correct answer: A. Ovarian teratoma
Explanation
Anti-NMDAR encephalitis is strongly associated with ovarian teratomas in women, found in approximately 58 percent of females over 18 years. CT or ultrasound of the pelvis should be performed routinely. Removal of the teratoma improves outcomes and reduces relapse. Pituitary adenoma and cerebellar hemangioblastoma are not associated. Thymic changes are seen in myasthenia gravis, not anti-NMDAR encephalitis.
Reference: Harrison's Principles of Internal Medicine, 21st ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.