Medicine · Neurology (Stroke, Epilepsy, Parkinson's, MS, MG, GBS, Meningitis)

A 30-year-old man presents with a generalized tonic-clonic seizure lasting 6 minutes. IV access is established. According to standard status epilepticus protocols, what is the first-line benzodiazepine of choice?

  • A Lorazepam IV
  • B Phenytoin IV
  • C Diazepam rectal gel
  • D Phenobarbital IV
Correct answer: A. Lorazepam IV

Explanation

IV Lorazepam is the first-line benzodiazepine for status epilepticus due to its rapid onset and longer duration of action compared to diazepam. Phenytoin or fosphenytoin is second-line. Rectal diazepam is used if IV access is unavailable.

Reference: Harrison's Principles of Internal Medicine, 21st ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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