On coronary angiography, TIMI-3 flow is defined as which of the following?

• A No antegrade flow beyond the occlusion
• B Contrast passes beyond the occlusion but fills the distal vessel slowly
• C Partial filling of the distal vessel with delayed clearance
• D Complete filling of the distal vessel with normal flow rate ✓

Explanation

TIMI-3 flow indicates complete perfusion of the distal coronary bed with normal flow velocity. TIMI-0 is no flow, TIMI-1 is penetration without perfusion, and TIMI-2 is partial perfusion with delayed filling. TIMI-3 flow is the therapeutic target of reperfusion therapy in STEMI.

Reference: Braunwald's Heart Disease, 12th ed.

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