Which of the following is an absolute contraindication to thrombolytic therapy in STEMI?
- A Aortic dissection ✓
- B Dental extraction performed 2 weeks ago
- C Prior ischemic stroke 8 months ago
- D Blood pressure of 160/100 mmHg at presentation
Correct answer: A. Aortic dissection
Explanation
Aortic dissection is an absolute contraindication to thrombolysis because it can cause fatal hemorrhage. BP of 160/100 mmHg is a relative contraindication. Prior stroke beyond 3 months is not an absolute contraindication. Recent dental extraction within 2 weeks is a relative contraindication depending on bleeding risk.
Reference: Braunwald's Heart Disease, 12th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.