Which extraintestinal manifestation of inflammatory bowel disease characteristically parallels intestinal disease activity?
- A Primary sclerosing cholangitis
- B Erythema nodosum ✓
- C Ankylosing spondylitis
- D Pyoderma gangrenosum
Correct answer: B. Erythema nodosum
Explanation
Erythema nodosum, peripheral arthritis and episcleritis are classified as type 1 (colitic) manifestations whose activity tracks with bowel inflammation, so they respond to treatment of the gut disease. Pyoderma gangrenosum may run an independent course despite being more common in Crohn disease. Ankylosing spondylitis and primary sclerosing cholangitis are type 2 manifestations that progress independently of intestinal activity, which kills those distractors.
Reference: Harrison's Principles of Internal Medicine, 21st ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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