Which cutaneous extraintestinal manifestation of inflammatory bowel disease characteristically runs parallel to the activity of the underlying bowel disease?
- A Pyoderma gangrenosum
- B Primary sclerosing cholangitis
- C Erythema nodosum ✓
- D Ankylosing spondylitis
Correct answer: C. Erythema nodosum
Explanation
Erythema nodosum is a reactive panniculitis whose activity tracks with gut inflammation and often resolves when the bowel disease is controlled. Pyoderma gangrenosum, primary sclerosing cholangitis and ankylosing spondylitis are classified as independent manifestations that pursue their own course regardless of intestinal activity. This parallel-versus-independent distinction is a standard examination point.
Reference: Harrison's Principles of Internal Medicine, 21st ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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