Medicine · Hypertension and Hypertensive Emergencies

A 32-year-old woman with hypertension has no atherosclerosis risk factors. Renal angiography shows a 'string of beads' appearance in the mid-to-distal renal artery. This finding is characteristic of:

  • A Atherosclerotic renal artery stenosis
  • B Takayasu arteritis
  • C Polyarteritis nodosa
  • D Fibromuscular dysplasia
Correct answer: D. Fibromuscular dysplasia

Explanation

The 'string of beads' appearance is pathognomonic for medial fibroplasia, the most common type of fibromuscular dysplasia. It typically affects young women and involves the mid-to-distal renal artery. Atherosclerotic stenosis is proximal and occurs in older patients with risk factors. Polyarteritis nodosa causes microaneurysms. Takayasu arteritis involves the aorta and its main branches.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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