The Ann Arbor staging system for Hodgkin lymphoma is supplemented by which suffix designating systemic B symptoms (fever >38°C, drenching night sweats, unexplained weight loss >10% in 6 months)?
- A Suffix 'E' for extranodal involvement
- B Suffix 'S' for splenic disease
- C Suffix 'B' ✓
- D Suffix 'X' for bulky disease only
Correct answer: C. Suffix 'B'
Explanation
In Ann Arbor staging (modified Cotswolds staging), suffix 'B' denotes the presence of any of three constitutional symptoms: fever >38°C, drenching night sweats, or unexplained weight loss >10% of body weight in the preceding 6 months. Absence of these symptoms is 'A'. 'E' denotes single extranodal site contiguous with a nodal region. 'S' denotes splenic involvement. 'X' denotes bulky disease (mediastinal mass >1/3 chest diameter or lymph node mass >10 cm).
Reference: Harrison's Principles of Internal Medicine, 21st ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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