Medicine · Heart Failure and Cardiomyopathies

A 55-year-old man presents with acute decompensated heart failure, blood pressure 85/60 mmHg, cold extremities, and oliguria. Pulmonary capillary wedge pressure is 28 mmHg and cardiac index is 1.8 L/min/m². Which hemodynamic profile does this represent, and what is the initial management strategy?

  • A Profile C (cold and wet): inotropes and consideration of mechanical circulatory support
  • B Profile B (warm and wet): vasodilators and diuretics
  • C Profile A (warm and wet): intravenous diuretics
  • D Profile D (cold and dry): cautious volume expansion
Correct answer: A. Profile C (cold and wet): inotropes and consideration of mechanical circulatory support

Explanation

The patient has low cardiac index (cold/perfusion failure) and elevated PCWP (wet/congestion), which is Profile A (cold and wet) in the Steimberg-Forrester classification. Profile A carries the worst prognosis. Management requires inotropes (dobutamine or milrinone) and evaluation for mechanical circulatory support (IABP, Impella, or LVAD). Diuretics alone risk further hemodynamic deterioration. Vasodilators are contraindicated with systolic BP <90 mmHg.

Reference: Harrison's Principles of Internal Medicine, 21st ed.

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