According to current ADA diagnostic criteria for diabetes mellitus, which single value confirms the diagnosis?
- A HbA1c of 6.5% or higher by NGSP-certified assay ✓
- B 2-hour plasma glucose of 160 mg/dL during a 75 g OGTT
- C Fasting plasma glucose of 110 mg/dL
- D Random plasma glucose of 140 mg/dL
Correct answer: A. HbA1c of 6.5% or higher by NGSP-certified assay
Explanation
The ADA thresholds are fasting glucose 126 mg/dL or more, 2-hour OGTT glucose 200 mg/dL or more, HbA1c 6.5% or more, and random glucose 200 mg/dL or more with classic symptoms. Fasting 110 mg/dL is impaired fasting glucose, 2-hour 160 mg/dL is impaired glucose tolerance, and random 140 mg/dL falls in the normal range, so none of these diagnose diabetes.
Reference: Harrison's Principles of Internal Medicine, 21st ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.