Medicine · Arrhythmias and Conduction Disorders (ECG, Tachycardia, Heart Block)

A 62-year-old man with paroxysmal AF and CHA2DS2-VASc score of 4 refuses anticoagulation due to recurrent falls. Which assessment tool should be used to evaluate bleeding risk before making the final decision on anticoagulation?

  • A HAS-BLED score; score >3 is an absolute contraindication to anticoagulation
  • B HAS-BLED score; high score identifies modifiable bleeding risk factors but is NOT an absolute contraindication
  • C HEMORR2HAGES score; mandates withholding anticoagulation if >4
  • D ATRIA score; anticoagulation should be stopped if score >10
Correct answer: B. HAS-BLED score; high score identifies modifiable bleeding risk factors but is NOT an absolute contraindication

Explanation

The HAS-BLED score (Hypertension, Abnormal liver/renal function, Stroke, Bleeding history/predisposition, Labile INR, Elderly >65, Drugs/alcohol) is recommended by ESC guidelines to identify modifiable bleeding risk factors rather than to deny anticoagulation. A score ≥3 identifies patients at higher bleeding risk in whom modifiable factors should be addressed (e.g., blood pressure control, cessation of NSAIDs, alcohol reduction) but is NOT a reason to withhold anticoagulation in those with high stroke risk. Withholding anticoagulation in AF with high CHA2DS2-VASc exposes patients to a greater net risk than bleeding.

Reference: Harrison's Principles of Internal Medicine, 21st ed.

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