A young adult presents with bilateral painless parotid swelling, low-grade fever, and anterior uveitis. Chest radiograph shows bilateral hilar lymphadenopathy. What is the most likely diagnosis?

• A Mumps
• B Mikulicz disease
• C Sjogren's syndrome
• D Heerfordt syndrome (uveoparotid fever) ✓

Explanation

Heerfordt syndrome is a presentation of sarcoidosis consisting of parotid enlargement, uveitis, fever, and frequently cranial nerve palsies, especially facial nerve palsy. Hilar lymphadenopathy on chest radiograph strongly supports sarcoidosis. Mumps is acute, painful, and self-limiting without uveitis or hilar nodes, while Sjogren's syndrome features dry eyes and dry mouth rather than fever and uveitis, which eliminates both distractors.

Reference: Scott-Brown's Otorhinolaryngology and Head and Neck Surgery, 8th ed.

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