A 28-year-old woman presents with bilateral painless parotid enlargement, low-grade fever, and painful red eyes. Chest radiograph shows bilateral hilar lymphadenopathy. The most likely diagnosis is:

• A Sjogren syndrome
• B Mikulicz disease
• C Heerfordt syndrome (uveoparotid fever) ✓
• D Recurrent juvenile parotitis

Explanation

Heerfordt syndrome is a presentation of sarcoidosis consisting of parotid enlargement, uveitis, facial nerve palsy, and fever. Hilar lymphadenopathy on chest radiograph strongly supports systemic sarcoidosis, and ACE levels or non-caseating granulomas on biopsy confirm it. Sjogren syndrome lacks fever, uveitis, and hilar nodes, and is defined by anti-Ro/La antibodies. Mikulicz disease is lacrimal and salivary enlargement without uveitis, and recurrent juvenile parotitis occurs in children with recurrent unilateral episodes.

Reference: Dhingra's Diseases of Ear, Nose and Throat, 8th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.