A Warthin tumor (papillary cystadenoma lymphomatosum) has a strong association with which risk factor, and what percentage of cases are bilateral?

• A Radiation exposure; 5–10% bilateral
• B Cigarette smoking; 10–15% bilateral ✓
• C Sjögren's syndrome; 25% bilateral
• D EBV infection; 40% bilateral

Explanation

Warthin tumor (the second most common benign salivary gland tumor after pleomorphic adenoma) is strongly associated with cigarette smoking, with smokers having an 8-fold increased risk. It occurs almost exclusively in the parotid gland (tail of parotid), and approximately 10–15% of cases are bilateral or multifocal. It is not associated with radiation, Sjögren's, or EBV. It arises from heterotopic salivary gland tissue trapped within intraparotid lymph nodes.

Reference: Dhingra Diseases of Ear, Nose and Throat, 7th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.