A 4-year-old child presents with recurrent respiratory papillomatosis. Which HPV serotypes are most commonly responsible for this condition?
- A HPV 6 and 11 ✓
- B HPV 16 and 18
- C HPV 31 and 33
- D HPV 1 and 2
Correct answer: A. HPV 6 and 11
Explanation
Recurrent respiratory papillomatosis (RRP) is caused by HPV types 6 and 11, the same types responsible for genital warts. It is acquired vertically during delivery through an infected birth canal. HPV 16 and 18 are high-risk oncogenic types associated with oropharyngeal carcinoma. RRP presents with hoarseness and stridor due to laryngeal papillomas.
Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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