Adenoid cystic carcinoma of the parotid is known for a characteristic spread pattern that explains its late recurrences and distant metastases years after treatment. This pattern is:
- A Perineural invasion with spread along nerve sheaths ✓
- B Lymphovascular invasion with early nodal metastasis
- C Skip lesions along the perichondrium
- D Haematogenous spread to regional skin
Correct answer: A. Perineural invasion with spread along nerve sheaths
Explanation
Adenoid cystic carcinoma is characterised by aggressive perineural invasion, spreading along nerve sheaths far beyond the visible tumor margin. This accounts for its high local recurrence rate, late distant metastases (particularly to lung), and facial nerve involvement. Despite this, regional lymph node metastasis is relatively infrequent compared to other salivary malignancies.
Reference: Dhingra Diseases of Ear, Nose and Throat, 7th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.