Warthin's tumor (papillary cystadenoma lymphomatosum) of the parotid gland characteristically:

• A Has high malignant potential and requires total parotidectomy
• B Occurs most commonly in women under 40
• C Arises from myoepithelial cells exclusively
• D Is bilateral in 10–15% of cases and shows increased uptake on Tc-99m pertechnetate scan ✓

Explanation

Warthin's tumor (lymphomatous papillary cystadenoma) is the second most common benign parotid tumor, occurring predominantly in elderly males and strongly associated with smoking. It is bilateral or multifocal in 10–15% of cases, a feature unique among parotid tumors. It shows characteristic 'hot spot' uptake on technetium-99m pertechnetate scintigraphy due to mitochondria-rich oncocytic epithelium. Malignant transformation is exceptionally rare. It arises from entrapped salivary duct epithelium within parotid lymph nodes.

Reference: Dhingra Diseases of Ear, Nose and Throat, 7th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.