Dermatology · Urticaria, Angioedema and Drug Eruptions

What is the most common morphological pattern of cutaneous adverse drug reaction?

  • A Urticaria
  • B Fixed drug eruption
  • C Maculopapular (morbilliform) exanthem
  • D Photosensitive eruption
Correct answer: C. Maculopapular (morbilliform) exanthem

Explanation

The maculopapular or morbilliform exanthem is by far the commonest drug eruption, typically beginning 7 to 14 days after starting a new drug as symmetric erythematous macules and papules that may become confluent. Ampicillin and amoxicillin are classic triggers, including the florid rash when given during infectious mononucleosis. Fixed drug eruptions, urticaria, and photosensitive reactions all occur but at far lower frequency.

Reference: Fitzpatrick's Dermatology, 9th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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