A 29-year-old man presents with a generalized, non-pruritic, copper-colored maculopapular rash involving the palms and soles. He also has painless, flat, moist lesions in the perianal region and generalized lymphadenopathy.

• A Secondary syphilis ✓
• B Pityriasis rosea
• C Lichen planus
• D Drug eruption

Explanation

Secondary syphilis classically presents with a copper-colored maculopapular rash on the palms and soles, along with condylomata lata (painless, flat, moist perianal lesions) and generalized lymphadenopathy. Lichen planus is violaceous and pruritic. Pityriasis rosea does not involve the palms and soles. Drug eruptions are usually pruritic and do not feature condylomata lata.

Reference: Harrison's Principles of Internal Medicine, 21st ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.