Biochemistry · Nutrition and Energy Metabolism (BMR, Starvation, Obesity, Metabolic Integration)

Which factor produces a genuine increase in basal metabolic rate?

  • A Fever
  • B Sleep
  • C Hypothyroidism
  • D Malnutrition
Correct answer: A. Fever

Explanation

Fever raises BMR by approximately 12 to 13% per degree Celsius rise in body temperature because of increased enzymatic activity and catecholamine drive. Sleep lowers BMR by about 10 to 15%, hypothyroidism reduces BMR by up to 40%, and prolonged malnutrition lowers BMR through loss of lean mass. Growth hormone and epinephrine also raise BMR, making fever the only correct option listed.

Reference: Guyton and Hall Textbook of Medical Physiology, 14th ed.

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