Which statement correctly pairs a porphyria with its mode of inheritance?

• A Acute intermittent porphyria: autosomal recessive
• B Hereditary coproporphyria: autosomal dominant ✓
• C Congenital erythropoietic porphyria: autosomal dominant
• D Porphyria cutanea tarda type I: X-linked dominant

Explanation

Hereditary coproporphyria, caused by coproporphyrinogen oxidase deficiency, is autosomal dominant. Acute intermittent porphyria and variegate porphyria are also autosomal dominant, so option A is wrong on inheritance. Congenital erythropoietic porphyria (Gunther disease) is autosomal recessive. Most sporadic porphyria cutanea tarda (type I) is acquired without germline inheritance, and the familial forms are autosomal dominant, making option D incorrect.

Reference: Harper's Illustrated Biochemistry, 32nd ed.

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