An enzyme catalyses the conversion of fructose 1,6 bisphosphate to dihydroxyacetone phosphate and glyceraldehyde 3 phosphate without the use of water or any transfer of a group to an acceptor. According to the IUBMB classification, this enzyme belongs to which class?

• A Lyase ✓
• B Transferase
• C Oxidoreductase
• D Isomerase

Explanation

Aldolase cleaves fructose 1,6 bisphosphate into two triose phosphates by a reverse aldol condensation. Lyases are enzymes that add or remove groups to form double bonds without hydrolysis, oxidation, or group transfer. Isomerase would apply only if the product had the same molecular formula, which fails here because one substrate becomes two products. Transferases move functional groups between molecules and oxidoreductases handle electron transfer, neither of which occurs in aldolase catalysis.

Reference: Lippincott Biochemistry, 8th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.