Cerebrospinal fluid (CSF) is primarily produced by which structure, and the volume of CSF produced per day is approximately:

• A Pia mater; approximately 150 mL/day
• B Arachnoid granulations; approximately 500 mL/day
• C Ependymal cells of the cerebral aqueduct; approximately 100 mL/day
• D Choroid plexus of all four ventricles; approximately 500 mL/day ✓

Explanation

CSF is produced primarily by the choroid plexus of all four ventricles (lateral, third, and fourth), with the lateral ventricles contributing the most. Approximately 500 mL is produced per day, yet the total CSF volume at any time is only about 150 mL, because the turnover rate is about 3–4 times per day. CSF is absorbed primarily through arachnoid granulations (villi) into the dural venous sinuses. The choroid plexus is a specialized vascular structure lined by modified ependymal cells that actively secrete CSF.

Reference: BD Chaurasia's Human Anatomy, 8th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.