Brown-Séquard syndrome results from hemisection of the spinal cord. Below the level of the lesion on the side of the lesion, one would find:

• A Loss of pain and temperature with preserved proprioception
• B Bilateral flaccid weakness with loss of all modalities
• C Ipsilateral loss of proprioception and vibration sense, AND ipsilateral spastic weakness; contralateral loss of pain and temperature ✓
• D Ipsilateral loss of pain and temperature with contralateral proprioceptive loss

Explanation

In Brown-Séquard syndrome (spinal cord hemisection), the ipsilateral side below the lesion shows: (1) corticospinal tract deficit — ipsilateral spastic weakness/UMN signs; (2) posterior column deficit — ipsilateral loss of proprioception, vibration, and discriminative touch. Contralateral side below the lesion shows: (3) spinothalamic deficit — contralateral loss of pain and temperature (spinothalamic fibers cross within 1–2 segments of entry before ascending). At the level of the lesion itself, there may be ipsilateral LMN signs and a band of ipsilateral pain/temperature loss from dorsal horn disruption.

Reference: BD Chaurasia's Human Anatomy, 8th ed.

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Written and medically reviewed by the StethoPrep medical team.