Anatomy · Neuroanatomy and Brain (Cerebrum, Brainstem, Cerebellum, Spinal Cord)

The substantia gelatinosa of Rolando in the spinal cord receives which primary afferent fibers and modulates which sensory modality?

  • A A-delta and C fibers; pain and temperature
  • B A-beta fibers; vibration and proprioception
  • C A-alpha fibers; muscle stretch
  • D A-delta fibers; pressure from skin
Correct answer: A. A-delta and C fibers; pain and temperature

Explanation

The substantia gelatinosa (lamina II of Rexed) at the apex of the dorsal horn receives small-diameter myelinated A-delta and unmyelinated C fibers carrying pain and temperature signals. It contains enkephalinergic interneurons that modulate pain transmission — the basis of the gate-control theory. A-beta fibers subserving touch and vibration primarily synapse in laminae III-V. The substantia gelatinosa surrounds the zone of Lissauer and is distinct from the nucleus proprius (laminae III-IV) below it.

Reference: BD Chaurasia's Human Anatomy, 8th ed.

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