A 35-year-old woman presents with recurrent postprandial vomiting and epigastric pain. CT shows pancreatic tissue completely encircling the second part of the duodenum. This anomaly results from:
- A Failure of the dorsal pancreatic bud to develop
- B Migration of the ventral bud around both sides of the duodenum before fusion with the dorsal bud ✓
- C Excessive apoptosis of the distal dorsal bud
- D Persistence of the left umbilical vein
Correct answer: B. Migration of the ventral bud around both sides of the duodenum before fusion with the dorsal bud
Explanation
The ventral pancreatic bud normally migrates clockwise around the duodenum to lie behind it and fuse with the dorsal bud. If the bilobed ventral bud migrates around both the right and left sides of the duodenum, the two lobes fuse dorsally and encircle it, producing annular pancreas with duodenal obstruction. The dorsal bud itself is unaffected, and umbilical vein persistence is irrelevant here.
Reference: Langman's Medical Embryology, 14th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.