Anatomy · Embryology (General, Pharyngeal Arches, GUT, CNS, Cardiovascular)

Meckel's diverticulum is a remnant of the vitello-intestinal (omphalomesenteric) duct. It contains heterotopic gastric mucosa in approximately 50% of symptomatic cases. The RULE OF 2s for Meckel's diverticulum includes all EXCEPT:

  • A 2 feet (60 cm) from the ileocaecal valve
  • B 2 inches long
  • C Presents before age 2 in 2 months of gestation origin
  • D 2% of the population affected
Correct answer: C. Presents before age 2 in 2 months of gestation origin

Explanation

The Rule of 2s for Meckel's diverticulum: 2% incidence, 2 feet (60 cm) proximal to ileocaecal valve, 2 inches long, 2 types of heterotopic mucosa (gastric and pancreatic), presents before age 2 years in symptomatic cases, and males to females ratio 2:1. 'Presents in 2 months of gestation origin' is not a rule of 2s component. It arises from incomplete obliteration of the vitello-intestinal duct at week 5–6 of embryonic development.

Reference: BD Chaurasia's Human Anatomy, 8th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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