Anatomy · Developmental Signalling and Molecular Embryology (HOX, SHH, Neural Crest)

Neural crest cells that migrate from the rhombencephalon to populate pharyngeal arch 1 give rise to all of the following EXCEPT:

  • A Meckel's cartilage
  • B Malleus and incus
  • C Tensor tympani muscle
  • D Stapes
Correct answer: C. Tensor tympani muscle

Explanation

Pharyngeal arch 1 (mandibular arch) neural crest cells contribute Meckel's cartilage (templates for mandible), the malleus and incus (from the dorsal end of Meckel's cartilage). The stapes arises from pharyngeal arch 2 (Reichert's cartilage). Tensor tympani is the muscle of arch 1, but it is mesodermal in origin (paraxial mesoderm), not from neural crest cells — the neural crest gives cartilage, bone, and connective tissue derivatives, not muscle.

Reference: BD Chaurasia's Human Anatomy, 8th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.

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