Cerebral autoregulation maintains constant CBF over a MAP range of approximately:

• A 40–80 mmHg
• B 60–200 mmHg
• C 50–150 mmHg ✓
• D 70–110 mmHg

Explanation

Cerebral autoregulation maintains cerebral blood flow (CBF) at approximately 50 mL/100 g/min over a MAP range of 50–150 mmHg through myogenic and metabolic mechanisms. Below 50 mmHg, CBF falls passively leading to ischaemia; above 150 mmHg, forced vasodilation causes hyperaemia and breakthrough cerebral oedema. In chronic hypertension, the autoregulatory curve shifts rightward; acute hypotension is then more dangerous. Volatile anaesthetics attenuate autoregulation in a dose-dependent manner.

Reference: Morgan & Mikhail's Clinical Anesthesiology, 6th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.