Rocuronium 0.6 mg/kg is used for tracheal intubation. Compared to succinylcholine 1 mg/kg, the onset of action of rocuronium at this dose is approximately:
- A 15-30 seconds
- B 90-120 seconds ✓
- C 45-60 seconds
- D 3-4 minutes
Correct answer: B. 90-120 seconds
Explanation
Rocuronium at 0.6 mg/kg has an onset of approximately 90-120 seconds. Succinylcholine at 1 mg/kg acts within 45-60 seconds. Rocuronium's lower potency (requires a larger molecular dose to achieve the same effect) accounts for its slower onset. At 1.2 mg/kg (RSI dose), rocuronium onset approaches that of succinylcholine.
Reference: Katzung Basic and Clinical Pharmacology, 15th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.