A mechanically ventilated patient in sinus rhythm, tidal volume 8 ml/kg, without spontaneous breaths, is assessed for fluid responsiveness. Which value of stroke volume variation best predicts a positive response to fluid challenge?
- A Less than 5%
- B Greater than 10 to 13% ✓
- C 5 to 8%
- D Stroke volume variation cannot be interpreted during mechanical ventilation
Correct answer: B. Greater than 10 to 13%
Explanation
In patients on controlled ventilation with tidal volume at least 8 ml/kg and in sinus rhythm, stroke volume variation above about 10 to 13% indicates significant preload dependence and predicts a rise in cardiac output after fluid loading. The same applies to pulse pressure variation greater than 12 to 13%. Low values indicate the patient is not fluid responsive, and the indices are valid only when the stated conditions are met.
Reference: Miller's Anesthesia, 9th ed.
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Written and medically reviewed by the StethoPrep medical team.