A 45-year-old patient undergoing elective laparoscopic cholecystectomy is maintained on sevoflurane. At sea level, the minimum alveolar concentration (MAC) of sevoflurane in an average 40-year-old adult is closest to:
- A 0.75%
- B 1.2%
- C 1.8% ✓
- D 2.05%
Correct answer: C. 1.8%
Explanation
The MAC of sevoflurane in a 40-year-old adult at sea level is approximately 2.0% (some sources cite 1.8–2.05%). Among the choices, 1.8% is the best match for standard adult MAC values cited in the anaesthesia literature. MAC represents the alveolar concentration at which 50% of patients do not move in response to a surgical skin incision. MAC decreases with increasing age, obesity, and certain co-administered drugs.
Reference: Morgan & Mikhail's Clinical Anesthesiology, 6th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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