For electroconvulsive therapy, which induction agent is classically associated with the LEAST increase in seizure threshold, preserving seizure quality?
- A Propofol
- B Methohexital ✓
- C Thiopentone
- D Etomidate
Correct answer: B. Methohexital
Explanation
Methohexital raises seizure threshold minimally and even facilitates seizures, making it the classical agent of choice for ECT. Propofol and thiopentone raise the seizure threshold more and shorten seizure duration, which may compromise treatment efficacy. Etomidate prolongs seizure duration but causes myoclonus and adrenal suppression, so it is reserved for patients needing haemodynamic stability rather than being the standard choice.
Reference: Miller's Anesthesia, 9th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.