The recommended endotracheal tube cuff pressure to prevent tracheal mucosal ischemia while maintaining an adequate seal is:

• A 50-60 cm H2O
• B 35-45 cm H2O
• C 20-30 cm H2O ✓
• D 10-15 cm H2O

Explanation

High-volume, low-pressure endotracheal tube cuffs should be maintained at 20-30 cm H2O. Pressures exceeding 30 cm H2O compress tracheal mucosal capillaries, causing ischemia and potential tracheal stenosis, while pressures below 20 cm H2O risk inadequate seal and aspiration. The value 35-45 cm H2O exceeds the safe threshold and can cause mucosal damage. Cuff pressure should be measured routinely with a manometer.

Reference: Miller's Anesthesia, 9th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.